Prognostic impact of trisomy 21 in follicular lymphoma
نویسندگان
چکیده
منابع مشابه
Prognostic factors in follicular lymphoma.
Follicular lymphoma (FL) is one of the most common types of non-Hodgkin's lymphoma. It is usually diagnosed at an advanced stage, for which many treatment options exist, however, no curative standard therapy has been identified. The outcome is highly variable with a median survival of approximately 10 years. The life expectancy of patients with FL has been extended with the use of rituximab, a ...
متن کاملFollicular lymphoma international prognostic index 2: a new prognostic index for follicular lymphoma developed by the international follicular lymphoma prognostic factor project.
PURPOSE The aim of the F2 study was to verify whether a prospective collection of data would enable the development of a more accurate prognostic index for follicular lymphoma (FL) by using parameters which could not be retrospectively studied before, and by choosing progression-free survival (PFS) as principal end point. PATIENTS AND METHODS Between January 2003 and May 2005, 1,093 patients ...
متن کاملFollicular lymphoma - treatment and prognostic factors
Follicular lymphoma is the second most frequent non-Hodgkin lymphoma accounting for about 10-20% of all lymphomas in western countries. The median age at diagnosis is 60 years old. The clinical presentation is usually characterized by asymptomatic peripheral adenopathy in cervical, axillary, inguinal and femoral regions. Treatment options for patients with naïve or recurrent follicular lymphoma...
متن کاملAssessing the prognostic impact of immune cell infiltrates in follicular lymphoma.
Sujith Samarasinghe is a pediatric hematologist at Great Ormond Street Hospital, London. He is a member of the EBMT SAA working party and his interests include childhood acquired aplastic anemia and bone marrow failure syndromes. Judith Marsh is Professor of Hematology at King’s College Hospital, London and is Chair of the EBMT SAA working party. Her main interests are the pathogenesis and trea...
متن کاملPrognostic value of chromosomal abnormalities in follicular lymphoma.
The t(14;18)(q32;q21) chromosomal translocation is observed in more than 75% of cases of follicular lymphoma. Several additional chromosomal abnormalities, which might contribute to tumor progression, have also been described. However, prognostic implications of cytogenetic features in follicular lymphoma have not been clearly established. In an attempt to correlate cytogenetic findings with cl...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2018
ISSN: 0007-1048,1365-2141
DOI: 10.1111/bjh.15664